McGuire drew early attention with depth-edge potential, showing speed and run defense acumen as part of Cleveland’s robust D-line rotation.

McGuire logged limited defensive time with no notable box-score stats, but his presence in the rotation signals Cleveland’s commitment to youth on the defensive line. He could grow into more snaps as the year progresses.

Isaiah McGuire has emerged as a significant contributor to the Browns' pass rush this season, showcasing his potential with a 74.2 overall grade, which ranks 12th among defensive linemen with 100 or more snaps. His performance includes 12 pressures on just 83 pass-rushing snaps, and he has excelled against the run, posting an impressive 89.9 run defense grade with five stops.

With Alex Wright out for the season, Isaiah McGuire is stepping into a larger role on the defense. He recorded six tackles and half a sack against the Bengals, bringing his season total to 12 tackles. As the Browns may look to trade other defensive linemen, McGuire's playing time is expected to increase, providing him with a crucial opportunity to prove himself after being selected in the fourth round of the 2023 NFL Draft. His performance will be closely watched as he takes on more responsibility in the second half of the season.

Isaiah McGuire is inactive for the Browns' matchup against the Dallas Cowboys, joining several other players on the sidelines for the game.